Peyronie's Disease - the blog: Proteomics in Peyronie's Disease - including a review of gene profiling in PD: "As I wrote a couple of days ago, even an area as understudied as Peyronie's can advance quickly when new instruments are brought to bear on old questions. Proteomics is all the rage in our post-genomic era, but besides the faddish topic the article claims to have reviewed the full literature on gene profiling in PD (of course that probably took about 3 hours)."Coincidentally, I've since had to do a review of protein network research and disease definition.
I now understand that one of the promises of protein networks is the ability to redefine diseases, which includes grouping differing syndromes into single disease classes and dividing a disease into subtypes -- or eliminating the disease/syndrome altogether. Protein networks, in other words, may do for our understanding of disease in humans what DNA research has done for defining and redefining species.
So this research may, for example, tell us if there really are important relationship between Peyronie's, Duputren's and other disorders of fibrosis.
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